In order to analyze flood damage mitigation effects, it is necessary not only to analyze inundation areas and depth through hydraulic and hydrological analysis but also to estimate flood damages. Flood damages of structure and contents of buildings are generally analyzed according to the flood depth. In this study, we developed and applied flood depth-damage functions for the school buildings based on actual damage data. In addition, the development and modification procedure of flood depth-damage functions for school buildings is presented in this paper, and the developed damage functions are verified by comparing them with the existing method. It is expected that the process of developing and applying flood depth-damage functions presented in this study can be used in the cost benefit analysis of flood damage mitigation measures.